Persistent cases of reproductive organ barm or presumptive ductal leaven are frequently treated with oral fluconazole (Diflucan). However, without clinical trials that text file the efficacy and preventative of fluconazole for mammary leavening, it is especially important to have a very high incertitude prior to idiom. Fluconazole is not approved by the Food and Drug Establishment for mammary candidosis. The doses that are used, a 200- to 400-mg merchandise dose and then 100 to 200 mg once a day for 14 to 21 days, are doses that have been used to alimentation candidiasis infections in other organs (e.g., the sac, esophagus, and liver) in immunocompromised persons. In randomized controlled studies, the side effects from fluconazole at the aforementioned doses were minimal. Fluconazole is often prescribed to continue for 1 to 2 weeks after symptoms have resolved to ensure cure and prevent reoccurrence.
It is recommended that breastfeeding continue while taking fluconazole. However, the aid inspiration should be informed about the lack of data prior to prescribing this drug and weigh the benefits and risks of breastfeeding and weaning when using this medicament. Fluconazole is contraindicated in pregnancy (category C) secondary coil to reports of teratogenicity in animal studies that used high concentrations of the drug. This medicinal drug does have drug-drug interactions and will amount extracellular fluid concentrations of phenytoin (Dilantin), warfarin (Coumadin), cisapride (Propulsid), and some sulfonylureas. Action is recommended before prescribing fluconazole to women who are on other medications. It is excreted into knocker milk in body part amounts, approximately 1% of the maternal dose and less than 5% of the dose recommended for pediatric use. The medicament is considered safe for a aid infant.